Targeted Mutation of the Mouse Grp94 Gene Disrupts Development and Perturbs Endoplasmic Reticulum Stress Signaling

Glucose-regulated protein 94 (GRP94) is one of the most abundant endoplasmic reticulum (ER) resident proteins and is the ER counterpart of the cytoplasmic heat shock protein 90 (HSP90). GRP94, a component of the GRP78 chaperone system in protein processing, has pro-survival properties with implicate...

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Bibliografiska uppgifter
Huvudupphovsmän: Mao, Changhui, Wang, Miao, Luo, Biquan, Wey, Shiuan, Dong, Dezheng, Wesselschmidt, Robin, Rawlings, Stephen, Lee, Amy S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2010
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877114/
https://ncbi.nlm.nih.gov/pubmed/20520781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010852
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