Preferential Amplification of CD8 Effector-T Cells after Transcutaneous Application of an Inactivated Influenza Vaccine: A Randomized Phase I Trial

BACKGROUND: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV. Following our recent study on vaccine penetration by targeting of vaccine to human hair follicular ducts su...

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Detalhes bibliográficos
Main Authors: Combadière, Behazine, Vogt, Annika, Mahé, Brice, Costagliola, Dominique, Hadam, Sabrina, Bonduelle, Olivia, Sterry, Wolfram, Staszewski, Shlomo, Schaefer, Hans, van der Werf, Sylvie, Katlama, Christine, Autran, Brigitte, Blume-Peytavi, Ulrike
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877091/
https://ncbi.nlm.nih.gov/pubmed/20520820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010818
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