Preferential Amplification of CD8 Effector-T Cells after Transcutaneous Application of an Inactivated Influenza Vaccine: A Randomized Phase I Trial

BACKGROUND: Current conventional vaccination approaches do not induce potent CD8 T-cell responses for fighting mostly variable viral diseases such as influenza, avian influenza viruses or HIV. Following our recent study on vaccine penetration by targeting of vaccine to human hair follicular ducts su...

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Dades bibliogràfiques
Autors principals: Combadière, Behazine, Vogt, Annika, Mahé, Brice, Costagliola, Dominique, Hadam, Sabrina, Bonduelle, Olivia, Sterry, Wolfram, Staszewski, Shlomo, Schaefer, Hans, van der Werf, Sylvie, Katlama, Christine, Autran, Brigitte, Blume-Peytavi, Ulrike
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877091/
https://ncbi.nlm.nih.gov/pubmed/20520820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010818
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