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Thrombospondin-1 null mice are resistant to hypoxia-induced pulmonary hypertension
BACKGROUND AND OBJECTIVE: Chronic hypoxia induces pulmonary hypertension in mice. Smooth muscle cell hyperplasia and medial thickening characterize the vasculature of these animals. Thrombospondin-1 null (TSP-1(-/-)) mice spontaneously develop pulmonary smooth muscle cell hyperplasia and medial thic...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877040/ https://ncbi.nlm.nih.gov/pubmed/20441584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1749-8090-5-32 |
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