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Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

Sac family phosphoinositide (PI) phosphatases are an essential family of CX(5)R(T/S)-based enzymes, involved in numerous aspects of cellular function such as PI homeostasis, cellular signalling, and membrane trafficking. Genetic deletions of several Sac family members result in lethality in animal m...

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Main Authors: Manford, Andrew, Xia, Tian, Saxena, Ajay Kumar, Stefan, Christopher, Hu, Fenghua, Emr, Scott D, Mao, Yuxin
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876947/
https://ncbi.nlm.nih.gov/pubmed/20389282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.57
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