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Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function

Sac family phosphoinositide (PI) phosphatases are an essential family of CX(5)R(T/S)-based enzymes, involved in numerous aspects of cellular function such as PI homeostasis, cellular signalling, and membrane trafficking. Genetic deletions of several Sac family members result in lethality in animal m...

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Detalhes bibliográficos
Main Authors: Manford, Andrew, Xia, Tian, Saxena, Ajay Kumar, Stefan, Christopher, Hu, Fenghua, Emr, Scott D, Mao, Yuxin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876947/
https://ncbi.nlm.nih.gov/pubmed/20389282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.57
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