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Enzyme-linked enzyme binding assay for Pin1 WW domain ligands
Peptidyl prolyl cis-trans isomerase (PPIase) interacting with NIMA-1 (Pin1) catalyzes the cis-trans isomerization of pSer/pThr–Pro amide bonds. Pin1 is a two-domain protein that represents a promising target for the treatment of cancer. Both domains of Pin1 bind the pSer/pThr–Pro motif; PPIase enzym...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2876714/ https://ncbi.nlm.nih.gov/pubmed/20230769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.03.018 |
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