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Lipin 1 Represses NFATc4 Transcriptional Activity in Adipocytes To Inhibit Secretion of Inflammatory Factors

Lipin 1 is a bifunctional protein that regulates gene transcription and, as a Mg(2+)-dependent phosphatidic acid phosphatase (PAP), is a key enzyme in the biosynthesis of phospholipids and triacylglycerol. We describe here the functional interaction between lipin 1 and the nuclear factor of activate...

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Bibliografski detalji
Glavni autori: Kim, Hyun Bae, Kumar, Anil, Wang, Lifu, Liu, Guang-Hui, Keller, Susanna R., Lawrence, John C., Finck, Brian N., Harris, Thurl E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876672/
https://ncbi.nlm.nih.gov/pubmed/20385772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01671-09
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