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Alterations in Hepatic Metabolism in fld Mice Reveal a Role for Lipin 1 in Regulating VLDL-Triacylglyceride Secretion

OBJECTIVE: Lipin 1 controls fatty acid metabolism in the nucleus as a transcriptional regulator and in the cytosol as an enzyme catalyzing the penultimate step in phosphoglycerol triacylglyceride (TAG) synthesis. We sought to evaluate the effects of lipin 1 on hepatic TAG synthesis and secretion by...

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Detalhes bibliográficos
Main Authors: Chen, Zhouji, Gropler, Matthew C., Norris, Jin, Lawrence, John C., Harris, Thurl E., Finck, Brian N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2655237/
https://ncbi.nlm.nih.gov/pubmed/18669885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.171538
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