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Through Its Nonstructural Protein NS1, Parvovirus H-1 Induces Apoptosis via Accumulation of Reactive Oxygen Species

The rat parvovirus H-1 (H-1PV) attracts high attention as an anticancer agent, because it is not pathogenic for humans and has oncotropic and oncosuppressive properties. The viral nonstructural NS1 protein is thought to mediate H-1PV cytotoxicity, but its exact contribution to this process remains u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hristov, Georgi, Krämer, Melanie, Li, Junwei, El-Andaloussi, Nazim, Mora, Rodrigo, Daeffler, Laurent, Zentgraf, Hanswalter, Rommelaere, Jean, Marchini, Antonio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876649/
https://ncbi.nlm.nih.gov/pubmed/20375165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01797-09
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