Interleukin-15 Is Critical in the Pathogenesis of Influenza A Virus-Induced Acute Lung Injury

Highly pathogenic influenza A viruses cause acute severe pneumonia to which the occurrence of “cytokine storm” has been proposed to contribute. Here we show that interleukin-15 (IL-15) knockout (KO) mice exhibited reduced mortality after infection with influenza virus A/FM/1/47 (H1N1, a mouse-adapte...

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Detalhes bibliográficos
Main Authors: Nakamura, Risa, Maeda, Naoyoshi, Shibata, Kensuke, Yamada, Hisakata, Kase, Tetsuo, Yoshikai, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876592/
https://ncbi.nlm.nih.gov/pubmed/20335267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02030-09
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