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Interleukin-21 Induces Short-Lived Effector CD8(+) T Cells but Does Not Inhibit Their Exhaustion after Mycobacterium bovis BCG Infection in Mice
Interleukin 21 (IL-21) is a pleiotropic common cytokine receptor γ chain cytokine that promotes the effector functions of NK cells and CD8(+) T cells and inhibits CD8(+) T cell exhaustion during chronic infection. We found that the absolute number of short-lived effector CD8(+) T cells (SLECs) (KLRG...
Gorde:
| Argitaratua izan da: | Infect Immun |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Society for Microbiology
2018
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6056876/ https://ncbi.nlm.nih.gov/pubmed/29844233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00147-18 |
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