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Use of the Cre-lox Recombination System To Investigate the lp54 Gene Requirement in the Infectious Cycle of Borrelia burgdorferi

Borrelia burgdorferi, the causative agent of Lyme disease, has a complex genome consisting of a linear chromosome and up to 21 linear and circular plasmids. These plasmids encode numerous proteins critical to the spirochete's infectious cycle and many hypothetical proteins whose functions and r...

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Autores principales: Bestor, Aaron, Stewart, Philip E., Jewett, Mollie W., Sarkar, Amit, Tilly, Kit, Rosa, Patricia A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876536/
https://ncbi.nlm.nih.gov/pubmed/20231410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01059-09
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