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Pharmacokinetic-Pharmacodynamic-Model-Guided Doripenem Dosing in Critically Ill Patients

The growing number of infections caused by multidrug-resistant pathogens has prompted a more rational use of available antibiotics given the paucity of new, effective agents. Monte Carlo simulations were utilized to determine the appropriateness of several doripenem dosing regimens based on the prob...

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Autors principals: Samtani, Mahesh N., Flamm, Robert, Kaniga, Koné, Nandy, Partha
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876367/
https://ncbi.nlm.nih.gov/pubmed/20385857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01843-09
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