Reappraisal of the Optimal Dose of Meropenem in Critically Ill Infants and Children: a Developmental Pharmacokinetic-Pharmacodynamic Analysis

Data of developmental pharmacokinetics (PK) of meropenem in critically ill infants and children with severe infections are limited. We assessed the population PK and defined the appropriate regimen to optimize treatment in this population based on developmental PK-pharmacodynamic (PD) analysis. Bloo...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Wang, Ze-Ming, Chen, Xiao-Yu, Bi, Jing, Wang, Mei-Ying, Xu, Bao-Ping, Tang, Bo-Hao, Li, Cen, Zhao, Wei, Shen, A-Dong
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526843/
https://ncbi.nlm.nih.gov/pubmed/32513801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-20
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