Reappraisal of the Optimal Dose of Meropenem in Critically Ill Infants and Children: a Developmental Pharmacokinetic-Pharmacodynamic Analysis

Data of developmental pharmacokinetics (PK) of meropenem in critically ill infants and children with severe infections are limited. We assessed the population PK and defined the appropriate regimen to optimize treatment in this population based on developmental PK-pharmacodynamic (PD) analysis. Bloo...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Wang, Ze-Ming, Chen, Xiao-Yu, Bi, Jing, Wang, Mei-Ying, Xu, Bao-Ping, Tang, Bo-Hao, Li, Cen, Zhao, Wei, Shen, A-Dong
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2020
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526843/
https://ncbi.nlm.nih.gov/pubmed/32513801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-20
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