Reappraisal of the Optimal Dose of Meropenem in Critically Ill Infants and Children: a Developmental Pharmacokinetic-Pharmacodynamic Analysis

Data of developmental pharmacokinetics (PK) of meropenem in critically ill infants and children with severe infections are limited. We assessed the population PK and defined the appropriate regimen to optimize treatment in this population based on developmental PK-pharmacodynamic (PD) analysis. Bloo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Wang, Ze-Ming, Chen, Xiao-Yu, Bi, Jing, Wang, Mei-Ying, Xu, Bao-Ping, Tang, Bo-Hao, Li, Cen, Zhao, Wei, Shen, A-Dong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Pharmacology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7526843/
https://ncbi.nlm.nih.gov/pubmed/32513801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00760-20
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