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The role of oxygen availability in embryonic development and stem cell function

Low levels of oxygen (O(2)) occur naturally in developing embryos. Cells respond to their hypoxic microenvironment by stimulating several hypoxia-inducible factors (and other molecules that mediate O(2) homeostasis), which then coordinate the development of the blood, vasculature, placenta, nervous...

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Bibliographic Details
Main Authors: Simon, M. Celeste, Keith, Brian
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876333/
https://ncbi.nlm.nih.gov/pubmed/18285802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm2354
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