MHC I Stabilizing Potential of Computer-Designed Octapeptides

Experimental results are presented for 180 in silico designed octapeptide sequences and their stabilizing effects on the major histocompatibility class I molecule H-2K(b). Peptide sequence design was accomplished by a combination of an ant colony optimization algorithm with artificial neural network...

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Detalhes bibliográficos
Main Authors: Wisniewska, Joanna M., Jäger, Natalie, Freier, Anja, Losch, Florian O., Wiesmüller, Karl-Heinz, Walden, Peter, Wrede, Paul, Schneider, Gisbert, Hiss, Jan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2876253/
https://ncbi.nlm.nih.gov/pubmed/20508831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2010/396847
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