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Microglial ablation and lipopolysaccharide preconditioning affects pilocarpine-induced seizures in mice

Activated microglia have been associated with neurodegeneration in patients and in animal models of Temporal Lobe Epilepsy (TLE), however their precise functions as neurotoxic or neuroprotective is a topic of significant investigation. To explore this, we examined the effects of pilocarpine induced...

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Detalhes bibliográficos
Main Authors: Mirrione, Martine M., Konomos, Dorothy K., Gravanis, Iordanis, Dewey, Stephen L., Aguzzi, Adriano, Heppner, Frank L., Tsirka, Stella E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875881/
https://ncbi.nlm.nih.gov/pubmed/20382223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2010.04.001
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