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Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas

Tumor Suppressor genes (TSGs) often locate at chromosomal regions with frequent deletions in tumors. Loss of 16q23 occurs frequently in multiple tumors, indicating the presence of critical TSGs at this locus, such as the well-studied WWOX. Herein we found that ADAMTS18, located next to WWOX, was sig...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Jin, Hongchuan, Wang, Xian, Ying, Jianming, Wong, Ada Ho Yan, Li, Hongyu, Lee, Kwan Yeung, Srivastava, Gopesh, Chan, Anthony TC, Yeo, Winnie, Ma, Brigette BY, Putti, Thomas C, Lung, Maria L, Shen, Zhong-Ying, Xu, Li-Yan, Langford, Cordelia, Tao, Qian
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: 2007
বিষয়গুলি:
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875853/
https://ncbi.nlm.nih.gov/pubmed/17546048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210559
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