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Epigenetic identification of ADAMTS18 as a novel 16q23.1 tumor suppressor frequently silenced in esophageal, nasopharyngeal and multiple other carcinomas

Tumor Suppressor genes (TSGs) often locate at chromosomal regions with frequent deletions in tumors. Loss of 16q23 occurs frequently in multiple tumors, indicating the presence of critical TSGs at this locus, such as the well-studied WWOX. Herein we found that ADAMTS18, located next to WWOX, was sig...

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Detalhes bibliográficos
Main Authors: Jin, Hongchuan, Wang, Xian, Ying, Jianming, Wong, Ada Ho Yan, Li, Hongyu, Lee, Kwan Yeung, Srivastava, Gopesh, Chan, Anthony TC, Yeo, Winnie, Ma, Brigette BY, Putti, Thomas C, Lung, Maria L, Shen, Zhong-Ying, Xu, Li-Yan, Langford, Cordelia, Tao, Qian
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875853/
https://ncbi.nlm.nih.gov/pubmed/17546048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210559
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