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Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1(+/−) Mice: A Role of Lipid Mobilization and Inflammation

Mammalian sirtuin 1 (SIRT1) may control fatty acid homeostasis in liver. However, this possibility and underlying mechanism remain to be established. In this study, we addressed the issues by examining the metabolic phenotypes of SIRT1 heterozygous knockout (SIRT1(+/−)) mice. The study was conducted...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Xu, Fen, Gao, Zhanguo, Zhang, Jin, Rivera, Chantal A., Yin, Jun, Weng, Jianping, Ye, Jianping
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Endocrine Society 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875813/
https://ncbi.nlm.nih.gov/pubmed/20339025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1013
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