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Lack of SIRT1 (Mammalian Sirtuin 1) Activity Leads to Liver Steatosis in the SIRT1(+/−) Mice: A Role of Lipid Mobilization and Inflammation

Mammalian sirtuin 1 (SIRT1) may control fatty acid homeostasis in liver. However, this possibility and underlying mechanism remain to be established. In this study, we addressed the issues by examining the metabolic phenotypes of SIRT1 heterozygous knockout (SIRT1(+/−)) mice. The study was conducted...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xu, Fen, Gao, Zhanguo, Zhang, Jin, Rivera, Chantal A., Yin, Jun, Weng, Jianping, Ye, Jianping
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The Endocrine Society 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875813/
https://ncbi.nlm.nih.gov/pubmed/20339025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1013
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