Biofunctionalization of electrospun PCL-based scaffolds with perlecan domain IV peptide to create a 3-D pharmacokinetic cancer model

Because prostate cancer cells metastasize to bone and exhibit osteoblastic features (osteomimicry), the interrelationships between bone-specific microenvironment and prostate cancer cells at sites of bone metastasis are critical to disease progression. In this work the bone marrow microenvironment i...

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Bibliografiske detaljer
Main Authors: Hartman, Olga, Zhang, Chu, Adams, Elizabeth L., Farach-Carson, Mary C., Petrelli, Nicholas J., Chase, Bruce D., Rabolt, John F.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875366/
https://ncbi.nlm.nih.gov/pubmed/20417554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2010.03.017
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