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Endothelin-1 Induced Contractile Responses of Human Coronary Arterioles via Endothelin-A Receptors and PKC-α Signaling Pathways

BACKGROUND: We investigated the contractile function in responses to endothelin-1 (ET-1) in the human coronary microvasculature and the roles of endothelin receptors and protein kinase C-α (PKC-α) in these responses. METHODS: Human atrial tissue was harvested from patients undergoing cardiac surgery...

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Detalhes bibliográficos
Main Authors: Feng, Jun, Liu, Yuhong, Khabbaz, Kamal R., Hagberg, Robert, Sodha, Neel R., Osipov, Robert M., Sellke, Frank W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875281/
https://ncbi.nlm.nih.gov/pubmed/20079914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2009.11.016
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