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Activation of central CRF receptor 1 by cortagine results in enhanced passive coping with a naturalistic threat in mice

CRF receptor subtype 1 (CRF1), abundantly expressed in the central nervous system, has been implicated in defensive behavior in rodents. Pharmacological activation of CRF1 by peptidic agonists results in enhancement of anxiety-like behavior. However, receptor specificity of commonly used agonists wa...

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Bibliographic Details
Main Authors: Tovote, Philip, Farrokhi, Catherine Borna, Gonzales, Rachael M. K., Schnitzbauer, Udo, Blanchard, D. Caroline, Blanchard, Robert J., Spiess, Joachim
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875276/
https://ncbi.nlm.nih.gov/pubmed/20036073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2009.12.001
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