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Cortagine, a specific agonist of corticotropin-releasing factor receptor subtype 1, is anxiogenic and antidepressive in the mouse model

Two subtypes of the corticotropin-releasing factor (CRF) receptor, CRF(1) and CRF(2), differentially modulate brain functions such as anxiety and memory. To facilitate the analysis of their differential involvement, we developed a CRF(1)-specific peptidic agonist by synthesis of chimeric peptides de...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Tezval, Hossein, Jahn, Olaf, Todorovic, Cedomir, Sasse, Astrid, Eckart, Klaus, Spiess, Joachim
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC439000/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15192151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403159101
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