Electron Transport Chain Dysfunction in Neonatal Pressure-Overload Hypertrophy Precedes Cardiomyocyte Apoptosis Independent of Oxidative Stress

BACKGROUND: We have previously shown in a model of pressure overload hypertrophy that there is increased cardiomyocyte apoptosis during the transition from peak hypertrophy to ventricular decompensation. Electron transport chain dysfunction is believed to play a role in this process through the prod...

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Main Authors: Griffiths, Eric R., Friehs, Ingeborg, Scherr, Elisabeth, Poutias, Dimitrios, McGowan, Francis X., del Nido, Pedro J.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875266/
https://ncbi.nlm.nih.gov/pubmed/20038480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jtcvs.2009.08.060
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