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Human intronic enhancers control distinct sub-domains of Gli3 expression during mouse CNS and limb development

BACKGROUND: The zinc-finger transcription factor GLI3 is an important mediator of Sonic hedgehog signaling and crucial for patterning of many aspects of the vertebrate body plan. In vertebrates, the mechanism of SHH signal transduction and its action on target genes by means of activating or repress...

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Detalhes bibliográficos
Main Authors: Abbasi, Amir A, Paparidis, Zissis, Malik, Sajid, Bangs, Fiona, Schmidt, Ansgar, Koch, Sabine, Lopez-Rios, Javier, Grzeschik, Karl-Heinz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875213/
https://ncbi.nlm.nih.gov/pubmed/20426846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-10-44
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