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Slow non-specific accumulation of 2′-deoxy and 2′-O-methyl oligonucleotide probes at mitochondria in live cells

Molecular beacons (MBs) have the potential to provide a powerful tool for rapid RNA detection in living cells, as well as monitoring the dynamics of RNA expression in response to external stimuli. To exploit this potential, it is necessary to distinguish true signal from background signal due to non...

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Hlavní autoři: Rhee, Won Jong, Bao, Gang
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875028/
https://ncbi.nlm.nih.gov/pubmed/20147460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq050
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