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Translation inhibition reveals interaction of 2′-deoxy and 2′-O-methyl molecular beacons with mRNA targets in living cells

Understanding the interaction between oligonucleotide probes and RNA targets in living cells is important for biological and clinical studies of gene expression in vivo. Here, we demonstrate that starvation of cells and translation inhibition by blocking the mTOR or PI-3 kinase pathway could signifi...

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Dades bibliogràfiques
Autors principals: Nitin, Nitin, Rhee, Won Jong, Bao, Gang
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
Matèries:
RNA
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731902/
https://ncbi.nlm.nih.gov/pubmed/19528073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp517
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