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Translation inhibition reveals interaction of 2′-deoxy and 2′-O-methyl molecular beacons with mRNA targets in living cells

Understanding the interaction between oligonucleotide probes and RNA targets in living cells is important for biological and clinical studies of gene expression in vivo. Here, we demonstrate that starvation of cells and translation inhibition by blocking the mTOR or PI-3 kinase pathway could signifi...

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Bibliografiske detaljer
Main Authors: Nitin, Nitin, Rhee, Won Jong, Bao, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731902/
https://ncbi.nlm.nih.gov/pubmed/19528073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp517
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