Structure of the Rna15 RRM–RNA complex reveals the molecular basis of GU specificity in transcriptional 3′-end processing factors

Rna15 is a core subunit of cleavage factor IA (CFIA), an essential transcriptional 3′-end processing factor from Saccharomyces cerevisiae. CFIA is required for polyA site selection/cleavage targeting RNA sequences that surround polyadenylation sites in the 3′-UTR of RNA polymerase-II transcripts. RN...

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Bibliographic Details
Main Authors: Pancevac, Christina, Goldstone, David C., Ramos, Andres, Taylor, Ian A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2010
Subjects:
Structural Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875009/
https://ncbi.nlm.nih.gov/pubmed/20097654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq002
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