Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis

BACKGROUND AND PURPOSE: In various models vagus nerve activation has been shown to ameliorate intestinal inflammation, via nicotinic acetylcholine receptors (nAChRs) expressed on immune cells. As the α7 nAChR has been put forward to mediate this effect, we studied the effect of nicotine and two sele...

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Detalhes bibliográficos
Main Authors: Snoek, Susanne A, Verstege, Marleen I, van der Zanden, Esmerij P, Deeks, Nigel, Bulmer, David C, Skynner, Michael, Lee, Kevin, te Velde, Anje A, Boeckxstaens, Guy E, de Jonge, Wouter J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874854/
https://ncbi.nlm.nih.gov/pubmed/20423343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00699.x
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