Caspase Inhibitor Therapy Synergizes With Costimulation Blockade to Promote Indefinite Islet Allograft Survival

OBJECTIVE: Costimulation blockade has emerged as a selective nontoxic maintenance therapy in transplantation. However, these drugs must be combined with other immunomodulatory agents to ensure long-term graft survival. RESEARCH DESIGN AND METHODS: Recent work has demonstrated that caspase inhibitor...

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Hauptverfasser: Emamaullee, Juliet A., Davis, Joy, Pawlick, Rena, Toso, Christian, Merani, Shaheed, Cai, Sui-Xiong, Tseng, Ben, Shapiro, A.M. James
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2010
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874708/
https://ncbi.nlm.nih.gov/pubmed/20332344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0502
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