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TBC1D1 Regulates Insulin- and Contraction-Induced Glucose Transport in Mouse Skeletal Muscle

OBJECTIVE: TBC1D1 is a member of the TBC1 Rab-GTPase family of proteins and is highly expressed in skeletal muscle. Insulin and contraction increase TBC1D1 phosphorylation on phospho-Akt substrate motifs (PASs), but the function of TBC1D1 in muscle is not known. Genetic linkage analyses show a TBC1D...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: An, Ding, Toyoda, Taro, Taylor, Eric B., Yu, Haiyan, Fujii, Nobuharu, Hirshman, Michael F., Goodyear, Laurie J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874696/
https://ncbi.nlm.nih.gov/pubmed/20299473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-1266
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