3α-Androstanediol, but Not Testosterone, Attenuates Age-Related Decrements in Cognitive, Anxiety, and Depressive Behavior of Male Rats

Some hippocampally-influenced affective and/or cognitive processes decline with aging. The role of androgens in this process is of interest. Testosterone (T) is aromatized to estrogen, and reduced to dihydrotestosterone (DHT), which is converted to 5α-androstane, 3α, 17α-diol (3α-diol). To determine...

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Bibliographische Detailangaben
Hauptverfasser: Frye, Cheryl A., Edinger, Kassandra L., Lephart, Edwin D., Walf, Alicia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Research Foundation 2010
Schlagworte:
Neuroscience
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874398/
https://ncbi.nlm.nih.gov/pubmed/20552051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00015
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