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3α-Androstanediol, but Not Testosterone, Attenuates Age-Related Decrements in Cognitive, Anxiety, and Depressive Behavior of Male Rats

Some hippocampally-influenced affective and/or cognitive processes decline with aging. The role of androgens in this process is of interest. Testosterone (T) is aromatized to estrogen, and reduced to dihydrotestosterone (DHT), which is converted to 5α-androstane, 3α, 17α-diol (3α-diol). To determine...

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Detalhes bibliográficos
Main Authors: Frye, Cheryl A., Edinger, Kassandra L., Lephart, Edwin D., Walf, Alicia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874398/
https://ncbi.nlm.nih.gov/pubmed/20552051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnagi.2010.00015
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