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Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

In this report, we demonstrate the sequence-specific suppression of viral expression in T cells chronically infected with human immunodeficiency virus 1 (HIV-1), using antisense phosphorothioate oligodeoxynucleotides. As a target for antisense intervention, we used the HIV-1 gene rev, which is essen...

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Autors principals: Matsukura, M, Zon, G, Shinozuka, K, Robert-Guroff, M, Shimada, T, Stein, C A, Mitsuya, H, Wong-Staal, F, Cohen, J S, Broder, S
Format: Artigo
Idioma:Inglês
Publicat: 1989
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC287427/
https://ncbi.nlm.nih.gov/pubmed/2471199
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