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Regulation of viral expression of human immunodeficiency virus in vitro by an antisense phosphorothioate oligodeoxynucleotide against rev (art/trs) in chronically infected cells.

In this report, we demonstrate the sequence-specific suppression of viral expression in T cells chronically infected with human immunodeficiency virus 1 (HIV-1), using antisense phosphorothioate oligodeoxynucleotides. As a target for antisense intervention, we used the HIV-1 gene rev, which is essen...

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Uloženo v:
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Matsukura, M, Zon, G, Shinozuka, K, Robert-Guroff, M, Shimada, T, Stein, C A, Mitsuya, H, Wong-Staal, F, Cohen, J S, Broder, S
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1989
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2471199/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.11.4244
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