Mouse/human chimeric monoclonal antibody in man: kinetics and immune response.

A mouse/human chimeric monoclonal antibody (mAb) composed of the variable regions of murine 17-1A mAb and the constant regions of human IgG-1K immunoglobulin was administered to 10 patients with metastatic colon cancer. Four patients received single infusion of 10 mg (n = 2) or 40 mg (n = 2). Six pa...

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Dettagli Bibliografici
Autori principali: LoBuglio, A F, Wheeler, R H, Trang, J, Haynes, A, Rogers, K, Harvey, E B, Sun, L, Ghrayeb, J, Khazaeli, M B
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1989
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC287422/
https://ncbi.nlm.nih.gov/pubmed/2726771
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