Mouse/human chimeric monoclonal antibody in man: kinetics and immune response.

A mouse/human chimeric monoclonal antibody (mAb) composed of the variable regions of murine 17-1A mAb and the constant regions of human IgG-1K immunoglobulin was administered to 10 patients with metastatic colon cancer. Four patients received single infusion of 10 mg (n = 2) or 40 mg (n = 2). Six pa...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	LoBuglio, A F, Wheeler, R H, Trang, J, Haynes, A, Rogers, K, Harvey, E B, Sun, L, Ghrayeb, J, Khazaeli, M B
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1989
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC287422/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2726771/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.11.4220
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