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Conformational and oligomeric effects on the cysteine pK(a) of typaredoxin peroxidase

Typical 2-Cys peroxiredoxins (Prxs) are peroxidases which regulate cell signaling pathways, apoptosis, and differentiation. These enzymes are obligate homodimers, and can form decamers in solution. During catalysis, Prxs exhibit cysteine-dependent reactivity which requires the deprotonation of the p...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Yuan, Ye, Knaggs, Michael H., Poole, Leslie B., Fetrow, Jacquelyn S., Salsbury, Freddie R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874197/
https://ncbi.nlm.nih.gov/pubmed/20476795
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