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Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions

Cryo-electron microscopy produces 3D density maps of molecular machines, which consist of various molecular components such as proteins and RNA. Segmentation of individual components in such maps is a challenging task, and is mostly accomplished interactively. We present an approach based on the imm...

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Detalhes bibliográficos
Main Authors: Pintilie, Grigore D., Zhang, Junjie, Goddard, Thomas D, Chiu, Wah, Gossard, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874196/
https://ncbi.nlm.nih.gov/pubmed/20338243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2010.03.007
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