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The Constitutive Activity of Epidermal Growth Factor Receptor vIII Leads to Activation and Differential Trafficking of Wild-type Epidermal Growth Factor Receptor and erbB2
A constitutively active epidermal growth factor receptor (EGFR) mutant, EGFR variant III (EGFRvIII), has been detected at high frequencies in certain human cancers. This study evaluated transactivation and trafficking of erbB family members as a result of constitutive EGFR activity in a cancer cell...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Histochemical Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2874185/ https://ncbi.nlm.nih.gov/pubmed/20159766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.2010.955104 |
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