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Resonance Assignment and Three-Dimensional Structure Determination of a Human Alpha-Defensin, HNP-1, by Solid-State NMR
Human α-defensins (HNPs) are immune defense mini-proteins that act by disrupting microbial cell membranes. Elucidating the three-dimensional structures of HNPs in lipid membranes is important for understanding their mechanisms of action. Using solid-state NMR, we have determined the three-dimensiona...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2873975/ https://ncbi.nlm.nih.gov/pubmed/20097206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.01.030 |
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