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Determination of Therapeutic Equivalence of Generic Products of Gentamicin in the Neutropenic Mouse Thigh Infection Model

BACKGROUND: Drug regulatory agencies (DRA) support prescription of generic products of intravenous antibiotics assuming therapeutic equivalence from pharmaceutical equivalence. Recent reports of deaths associated with generic heparin and metoprolol have raised concerns about the efficacy and safety...

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Detalhes bibliográficos
Main Authors: Zuluaga, Andres F., Agudelo, Maria, Cardeño, John J., Rodriguez, Carlos A., Vesga, Omar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873963/
https://ncbi.nlm.nih.gov/pubmed/20505762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010744
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