Eef1a2 Promotes Cell Growth, Inhibits Apoptosis and Activates JAK/STAT and AKT Signaling in Mouse Plasmacytomas

BACKGROUND: The canonical function of EEF1A2, normally expressed only in muscle, brain, and heart, is in translational elongation, but recent studies suggest a non-canonical function as a proto-oncogene that is overexpressed in a variety of solid tumors including breast and ovary. Transcriptional pr...

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Bibliographic Details
Main Authors: Li, Zhaoyang, Qi, Chen-Feng, Shin, Dong-Mi, Zingone, Adriana, Newbery, Helen J., Kovalchuk, Alexander L., Abbott, Catherine M., Morse, Herbert C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873962/
https://ncbi.nlm.nih.gov/pubmed/20505761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010755
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