Eef1a2 promotes cell growth, inhibits apoptosis and activates JAK/STAT and AKT signaling in mouse plasmacytomas.

The canonical function of EEF1A2, normally expressed only in muscle, brain, and heart, is in translational elongation, but recent studies suggest a non-canonical function as a proto-oncogene that is overexpressed in a variety of solid tumors including breast and ovary. Transcriptional profiling of a...

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Detalhes bibliográficos
Main Authors: Zhaoyang Li, Chen-Feng Qi, Dong-Mi Shin, Adriana Zingone, Helen J Newbery, Alexander L Kovalchuk, Catherine M Abbott, Herbert C Morse
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2010-05-01
Colecção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC2873962?pdf=render
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