Alzheimer's Disease Amyloid-β Links Lens and Brain Pathology in Down Syndrome

Down syndrome (DS, trisomy 21) is the most common chromosomal disorder and the leading genetic cause of intellectual disability in humans. In DS, triplication of chromosome 21 invariably includes the APP gene (21q21) encoding the Alzheimer's disease (AD) amyloid precursor protein (APP). Triplic...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Moncaster, Juliet A., Pineda, Roberto, Moir, Robert D., Lu, Suqian, Burton, Mark A., Ghosh, Joy G., Ericsson, Maria, Soscia, Stephanie J., Mocofanescu, Anca, Folkerth, Rebecca D., Robb, Richard M., Kuszak, Jer R., Clark, John I., Tanzi, Rudolph E., Hunter, David G., Goldstein, Lee E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873949/
https://ncbi.nlm.nih.gov/pubmed/20502642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0010659
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados