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A New Class of Molecular Targeted Radioprotectors: GSK-3β Inhibitors

PURPOSE: Development of new treatments is critical to effective protection against radiation-induced injury. Here we investigate the potential of developing small molecule inhibitors of GSK-3β, SB216763 or SB415286, as radioprotective agents to attenuate intestinal injury. METHODS AND MATERIALS: Sur...

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Bibliografiske detaljer
Main Authors: Thotala, Dinesh K., Geng, Ling, Dickey, Amy K., Hallahan, Dennis E., Yazlovitskaya, Eugenia M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2873869/
https://ncbi.nlm.nih.gov/pubmed/20117291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijrobp.2009.09.024
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