Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature

Despite wide margins and high dose irradiation, unresectable malignant glioma (MG) is less responsive to radiation and is uniformly fatal. We previously found that cytosolic phospholipase A2 (cPLA(2)) is a molecular target for radiosensitizing cancer through the vascular endothelium. Autotaxin (ATX)...

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Detalhes bibliográficos
Main Authors: Schleicher, Stephen M., Thotala, Dinesh K., Linkous, Amanda G., Hu, Rong, Leahy, Kathleen M., Yazlovitskaya, Eugenia M., Hallahan, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3140496/
https://ncbi.nlm.nih.gov/pubmed/21799791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0022182
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